Spinach Artichoke Grilled Cheese

Featured in: One-Pot Cozy Suppers

This spinach artichoke grilled cheese elevates a beloved classic with a savory, creamy filling. Fresh spinach and artichoke hearts blend with three cheeses for a rich, satisfying sandwich that comes together in just 25 minutes.

Prepare the filling by sautéing spinach until wilted, then combine with chopped artichokes, cream cheese, mozzarella, and Parmesan. Spread onto sourdough, butter the outside, and cook until the bread turns golden and the cheese melts into every bite.

Updated on Sun, 18 Jan 2026 10:49:00 GMT
Golden-brown Spinach Artichoke Grilled Cheese sandwiches sit on a rustic board, oozing creamy filling. Pin to Board
Golden-brown Spinach Artichoke Grilled Cheese sandwiches sit on a rustic board, oozing creamy filling. | embersprig.com

The smell of garlic hitting warm butter is what convinced me to try making this sandwich on a Tuesday night when I was too tired to think. I had leftover artichoke dip in the fridge and a hunch that it would melt beautifully between sourdough slices. The first bite was so good I stood at the counter eating it instead of sitting down. Sometimes the best recipes happen when you stop overthinking and just trust your cravings.

I made these for my sister during one of her weekend visits, and she immediately asked if I had opened a café without telling her. We sat on the back porch with iced tea, and she declared it better than any grilled cheese she had paid twelve dollars for downtown. That kind of reaction makes you want to cook for people more often.

Ingredients

  • Mozzarella cheese: This is your melt factor, the cheese that stretches and binds everything into gooey perfection without overpowering the other flavors.
  • Cream cheese: Softened cream cheese makes the filling smooth and spreadable, almost like a warm dip that holds its shape inside the sandwich.
  • Parmesan cheese: A little Parmesan adds sharpness and depth, cutting through the richness with a nutty, salty edge.
  • Unsalted butter: Softened butter spreads easily on the bread and crisps up into a golden, crackling crust that makes every bite satisfying.
  • Fresh spinach: Spinach wilts down fast and adds color, earthiness, and a bit of nutrition without making the sandwich taste too virtuous.
  • Artichoke hearts: Chopped artichokes bring a tender, slightly tangy bite that balances the creaminess and makes the filling feel special.
  • Garlic clove: One small clove is enough to perfume the whole mixture without turning it into garlic bread.
  • Sourdough bread: Sourdough has the structure to hold up to a heavy filling and the tang to complement the richness of the cheese.
  • Salt, black pepper, and red pepper flakes: These seasonings wake up the filling and add just enough heat to keep things interesting.

Instructions

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Wilt the spinach:
Add the spinach to a medium skillet over medium heat with a splash of water, stirring until it softens and shrinks down in about a minute or two. Drain any extra moisture so your sandwich does not get soggy.
Mix the filling:
In a bowl, combine the wilted spinach, chopped artichokes, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if you like a little kick. Stir until everything is evenly blended and creamy.
Assemble the sandwiches:
Spread the spinach artichoke mixture generously onto two slices of sourdough, then top each with another slice to form two sandwiches. Press down gently so the filling settles.
Butter the bread:
Spread softened butter on the outside of each sandwich, covering the surface evenly so every bite gets crispy.
Grill until golden:
Heat a large nonstick skillet or griddle over medium heat and place the sandwiches in the pan. Cook for three to four minutes per side, pressing gently with a spatula, until the bread turns deep golden brown and the cheese melts into the filling.
Serve hot:
Remove the sandwiches from heat, slice them in half, and serve immediately while the cheese is still stretchy and warm.
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Fresh spinach and artichoke hearts meld with melted cheese inside crisp sourdough slices. Pin to Board
Fresh spinach and artichoke hearts meld with melted cheese inside crisp sourdough slices. | embersprig.com

One rainy afternoon, I made this sandwich for lunch and ate it with a bowl of tomato soup, dipping each bite until the soup was gone. It felt like the kind of meal that makes you grateful to be inside, warm, and well fed. Sometimes comfort is just melted cheese and good bread.

Choosing Your Bread

Sourdough is ideal because it has a sturdy crumb and a slight tang that plays well with creamy, garlicky fillings. If you want something heartier, whole wheat or multigrain works beautifully and adds a nutty flavor. Just make sure the slices are thick enough to hold the filling without tearing when you flip them.

Making It Your Own

A handful of fresh basil stirred into the filling brings a bright, herbal note that makes the sandwich taste even more vibrant. Smoked paprika adds a subtle smokiness that deepens the flavor without overwhelming it. You could also toss in some sun dried tomatoes or swap mozzarella for fontina if you are feeling adventurous.

Serving and Pairing

This sandwich is perfect on its own, but it becomes a full meal when you serve it alongside tomato soup or a simple green salad with lemon vinaigrette. If you are feeding a crowd, cut the sandwiches into quarters and serve them as appetizers. They disappear fast.

  • Tomato soup is the classic pairing and never gets old.
  • A crisp salad with arugula and balsamic adds freshness and cuts the richness.
  • Serve with pickles or potato chips if you want something crunchy on the side.
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A gourmet Spinach Artichoke Grilled Cheese, paired with steaming tomato soup for cozy lunch. Pin to Board
A gourmet Spinach Artichoke Grilled Cheese, paired with steaming tomato soup for cozy lunch. | embersprig.com

This sandwich has become my go to whenever I want something that feels indulgent but comes together without fuss. I hope it becomes one of yours too.

Common Questions

Can I prepare the spinach artichoke filling ahead of time?

Yes, you can make the filling up to 2 days in advance. Store it in an airtight container in the refrigerator. Simply assemble and cook the sandwiches when ready to serve.

What bread works best for this sandwich?

Sourdough provides the best flavor and structure, but you can substitute with ciabatta, focaccia, or multigrain bread. Choose bread thick enough to contain the filling without tearing.

How do I prevent the cheese from leaking out while cooking?

Spread the filling evenly to the edges of the bread and press gently while cooking. Medium heat allows the cheese to melt slowly without bursting out. Use a spatula to flip carefully.

Can I add other vegetables to the filling?

Absolutely. Sautéed mushrooms, caramelized onions, roasted red peppers, or sun-dried tomatoes work beautifully. Ensure any added vegetables are drained well to prevent excess moisture.

What's the best way to serve this sandwich?

Slice diagonally and serve immediately while the cheese is still warm and melty. Pair with tomato soup, a simple salad, or pickles for a complete meal.

Can I make this dairy-free?

Yes, substitute dairy cheese with high-quality vegan alternatives and use dairy-free butter. Use vegan cream cheese for the filling. Results vary by brand, so choose ones that melt well.

Spinach Artichoke Grilled Cheese

Creamy spinach and artichoke filling between crisp golden sourdough slices. A gourmet twist on the classic comfort sandwich.

Prep Duration
15 min
Cook Duration
10 min
Overall Duration
25 min
Created by Lucas Rivera


Skill Level Easy

Cuisine Type American

Makes 2 Portions

Diet Preferences Vegetarian-Friendly

What You’ll Need

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

How To Make It

Step 01

Prepare the spinach: Heat a medium skillet over medium heat. Add chopped spinach with a splash of water and sauté for 1 to 2 minutes until wilted. Transfer to a colander and drain excess moisture thoroughly.

Step 02

Combine filling ingredients: In a mixing bowl, combine the drained spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, minced garlic, salt, pepper, and red pepper flakes if desired. Blend until well incorporated.

Step 03

Assemble sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough bread. Top each with a remaining bread slice to form two complete sandwiches.

Step 04

Butter the bread: Apply softened butter to the outside surfaces of all bread slices on both sandwiches.

Step 05

Cook the sandwiches: Heat a nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3 to 4 minutes per side, applying gentle pressure with a spatula, until bread achieves golden-brown color and cheese is fully melted.

Step 06

Finish and serve: Remove sandwiches from heat. Cut diagonally in half and serve immediately while warm.

Equipment Needed

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergy Details

Review ingredients for potential allergens and check with your healthcare provider as needed.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or tree nuts depending on cheese and bread brand sources

Nutrition Info (per serving)

Details listed are for reference only—please consult professionals for specific health needs.
  • Caloric Content: 430
  • Fats: 24 g
  • Carbohydrates: 39 g
  • Proteins: 16 g